Atherothrombosis & Coronary Artery Disease

Written by the world’s foremost authorities, this volume provides comprehensive coverage of current approaches to the prevention, diagnosis, and management of atherothrombosis and its coronary and noncoronary complications. This edition has been thoroughly updated, sharply focused on clinical information, and trimmed to one manageable volume.

Coverage begins with a review of risk factors and prevention, emphasising lipid abnormalities, hypertension, smoking, diabetes, and obesity. Subsequent sections examine the pathogenesis of atherosclerosis, markers and imaging, acute coronary syndromes, chronic stable angina, and noncoronary atherothrombosis. Clinical presentations, medical management, and the latest interventional strategies are included.

FEATURES:

* Includes coverage of risk factors and prevention; emphasizing lipid abnormalities, hypertension, smoking, diabetes and obesity

* Examines the pathogenesis of atherosclerosis, markers and imaging, acute coronary syndromes, chronic stable angina and noncoronary atherothrombosis.

* Includes clinical presentations, medical management and the latest interventional strategies

NEW TO THIS EDITION:

* More clinically oriented

* Trimmed to one manageable volume.

* Includes only the basic science that is clinically relevant

Contents

Ch 1 A Historical Perspective on Atherothrombosis and Coronary Artery Disease - W. Bruce Fye
Ch 2 Incidence, Prevalence, and Mortality of Coronary Artery Disease - William B. Kannel

Section I Major Risk Factors and Primary Prevention
Ch 3 Overview - Henry C. McGill, Jr. and C. A. McMahan

Lipid Abnormalities
Ch 4 Lipids, Nutrition, and Coronary Heart Disease - Scott M. Grundy
Ch 5 Genetic Dyslipoproteinemias - H. Brian Brewer, Jr. and Silvia Santamarian-Fojo
Ch 6 Structure and Function of the Plasma Lipoproteins and Their Receptors - John P. Kane
Ch 7 Plasma High Density Lipoproteins and Atherogenesis - Daniel Rader
Ch 8 Oxidized Lipoproteins and Atherosclerosis - Guy M. Chisolm
Ch 9 Lipoprotein - Angelo M. Scanu
Ch 10 Clinical Classifications - Thomas P. Bersot and Robert W. Mahley
Ch 11 Management and ATP III Guidelines - John A. Farmer and Antonio M. Gotto, Jr.
Ch 12 Impact of Management in Stabilization and Decrease in Cardiovascular Events - B. Greg Brown and Antonio M. Gotto, Jr.

Hypertension, Cigarette Smoking, Diabetes, Obesity and Others
Ch 13 Genetics and Mechanisms of Hypertension - Steven C. Hunt and Paul N. Hopkins
Ch 14 Renin Angiotensin System and Atherothrombotic Vascular Disease - Victor J. Dzau and Aram V. Chobanian
Ch 15 Clinical Classifications of Hypertension - Edward D. Frohlich
Ch 16 Management of Hypertension - Norman M. Kaplan
Ch 17 Hypertensive Heart Disease - Robert A. Phillips and Joseph A. Diamond
Ch 18 Cigarette Smoking and Atherothrombosis - Thomas Pickering and Lynn Clemow
Ch 19 Diabetes, Obesity, and the Metabolic Syndrome - Doron Aronson and Elliot J. Rayfield
Ch 20 Hormonal Replacement: Pros and Cons - Lori Mosca
Ch 21 Vitamins: Pros and Cons - Joan E. B. Fox

Section II Pathogenesis of Atherosclerosis
General Principles
Ch 22 Developmental Biology of the Vasculature - Margaret Kirby
Ch 23 Vasculogenesis - Peter Carmeliet
Ch 24 Embryogenesis of the Vascular System - Brant Weinstein
Ch 25 Mouse Models of Lipoprotein and Atherothrombosis - Andrew Plump
Ch 26 Genetics of Atherothrombotic Disease - Pierre Zoldhelyi

The Normal Artery
Ch 27 Vascular Endothelium - Paul E. DiCorleto
Ch 28 Role of Alterations in the Differentiated State of Smooth Muscle Cell in Atherothrombogenesis - Gary K. Owens
Ch 29 The Vascular Extracellular Matrix - Thomas N. Wight

The Lesions of Atherothrombosis
Ch 30 The Histological Classification of Atherosclerotic Lesions - Herbert C. Stary