Clinical Neuroimmunology

* Describes the role of the immune system in injury and repair of a wide array of neurological disorders
* Covers both concepts and their applications in a way which is relevant for clinicans and basic scientists
* Clinically orientated throughout with an emphasis on new therapies for established diseases

New to this edition

* New co-editor providing coverage of the role of anti-bodies in a wider array of neurological disorders than previously thought
* Over half of the book has been revised for this edition
* Covers the role of the immune system in injury and repair of a wide array of neurological disorders
* New chapters on neural regulation of the immune response and immune mediated protection and repair in the nervous system
* Introductory chapter by Byron H. Waksman, a major pioneer in the field of neuroimmunology
* Expanded presentations relating to MS, giving new insights and challenges to clinical treatments
* New chapter on regeneration in the CNS

Clinical Neurimmunology is the major reference text in the field, providing broad and comprehensive coverage of the interaction between the nervous and immune systems in both normal and diseased states. Understanding this interaction is fundamental to developing therapeutic approaches to disease and injury of the nervous system that are currently only marginally amenable to therapy. Neuroimmunology is a well-recognised and growing specialty world wide, both at the basic science and clinical level. It is a fast moving field and this is the most up to date text available. Chapters are dedicated to the role of the immune system in disorders affecting both the central and peripheral nervous systems, including important neurodegenerative diseases (such as multiple sclerosis and HIV-related neural degeneration) which cause life-long disability. Extensive coverage is given to a whole array of immune-directed therapies.

The book has a strong international team of well respected, high profile editors and authors. The first edition published to extensive and positive reviews and has established itself as the principal reference source in the field. This second edition summarizes recent advances in clinical neuroimmunology in a comprehensive and unbiased way.



1: Byron Waksman: A brief history of neuroimmunology
2: Jack Antel, Gary Birnbaum & Hans-Peter Hartung: Basics of immunology
3: Jack Antel, Gary Birnbaum & Hans-Peter Hartung: Assessing immune function in clinical neuroimmunologic disease
4: David Hafler: Principles of autoimmunity
5: Reinhold Hohfield, Bernard Hemmer & Hans-Peter Hartung: Principles of immunotherapy
5b: Matthew Wood: Organisation and development of the central nervous system
6: Burkhard Becher: Immunology properties of the CNS
7: Sam David & Steve Lacroix: Role of the immune response in neuroprotection and repair
8: Hans-Peter Hartung: Immunology properties of the PNS
9: Steven Hauser, Jorge Oksenberg & David Brassat: Genetics of immune-mediated neurologic diseases
10: Pierre Talbot: Principles of immune-virus interactions in the nervous system
11: Walter Pfister & Uwe Koedel: Immunity of bacterial infections
12: Trevor Owens & Iain Campbell: Animal models of neuroimmunologic disease
13: Robert Lisak & Alex Tselis: Acute disseminated encephalomyelitis
14: Bruce Trapp & Richard Ransohoff: Multiple Sclerosis - immunopathology
15: Ken Smith & Richard Evans: Multiple Sclerosis - effects of immune mediators on neurophysiologic function
16: Doug Arnold, Nicola de Stefano, Zografos Caramanos, Roger Gunn & Joseph Frank: Multiple Sclerosis - monitoring the immuno-biology by neuroimaging
17: Jack Antel & Gary Birnbaum: Clinical immunology
18: Hans-Peter Hartung, Bernard Hemmer & Bernd Kieseier: Multiple Sclerosis - immune-directed therapy
19: Hans-Peter Hartung, Bernard Hemmer & Bernd Kieseier: Acute Inflammatory Neuropathies
20: John Pollard: Chronic inflammatory neuropathies
21: Angela Vincent: Antibody mediated disorders of the neuromuscular junction
22: Marinos Dalakas: Inflammatory diseases of muscle
23: Chris Power & Guido van Marle: HIV infection and the nervous system
24: Steve Jacobson, Utano Tomaru & Yoshihisa Yamano: HTLV-1 infection and the nervous system
25: Andrew Pachner: Lyme disease
26: Josep Dalmau: Paraneoplastic syndromes
27: Norman Latov, Andreas Steck & Susanne Renaud: Paraproteinemic neuropathies
28: Aksel Siva, Ayse Altintas & Sabahattin Saip: Bechet's disease
29: Patrick McGeer & Edith McGeer: Role of neural-immune interactions in neurodegenerative diseases
30: Nicolas de Tribolet: CNS neoplastic diseases and the immune system
31: Paula Dore-Duffy & Rouman Balabanov: Vasculitis disorders of the nervous system
32: Esther Sternberg: Psycho-neuro immunology
33: Boris Zalc & Catherine Lubetzki: Regeneration of the CNS
34: Guido Stoll & John Hallenbeck: Immunological aspects of cerebal ischemia
35: Angela Vincent: Antibodies and CNS disorders
36: Jack Antel, Gary Birnbaum & Hans-Peter Hartung: Immunologic dictionary