Clinical Tuberculosis

Summary:
Over three previous editions, Clinical Tuberculosis has established itself as an indispensable guide to all aspects of tuberculosis diagnosis and treatment. This fully revised and updated fourth edition provides practical guidance to healthcare professionals involved in any aspect of patient management or disease control; chapters are included on epidemiology, pathology, immunology, disease presentation, diagnosis, treatment and management options.

The problem of TB associated with HIV infection is given special emphasis, as are the increasing problems of multi-drug resistant strains and environmentally opportunistic mycobacteria. Chapter authors have been hand-picked to represent the most up-to-date thinking in their particular subject areas, making Clinical Tuberculosis the essential reference work for the bookshelves of respiratory physicians, infectious disease specialists, public health workers and other individuals involved in the management and control of tuberculosis worldwide.

* A fully international authorship of the highest standard, selected by some of the worlds most distinguished authorities
* An emphasis throughout on providing clear, practical clinical advice
* Combines an historical and descriptive focus with the latest diagnostic and therapeutic information
* Contains integrated coverage of the basic science aspects of TB



Table of Contents:
PART 1 BACKGROUND
1 The history of tuberculosis from earliest times to the development of drugs
2 Epidemiology
PART 2 PATHOLOGY AND IMMUNOLOGY
3 Genotyping and its implications for transmission dynamics and tuberculosis
4 Mycobacterium tuberculosis: the organism
5 The diagnosis of tuberculosis
6 Immunodiagnostic tests
7 Histopathology
8 Human immune response to tuberculosis
PART 3 CLINICAL ASPECTS
9 Respiratory tuberculosis
10 Non-respiratory tuberculosis
11 Tuberculosis in childhood
PART 4 TREATMENT
12 Clinical pharmacology of the antituberculosis drugs
13 Chemotherapy including drug-resistant therapy and future developments
14 New developments in treatment
15 International standards for tuberculosis care: integrating tuberculosis care and control
16 The surgical management of tuberculosis and its complications
17 Directly observed therapy and other aspects of management of tuberculosis care
18 DOTS and DOTS-Plus
PART 5 TUBERCULOSIS IN SPECIAL SITUATIONS
19 The association between HIV and tuberculosis in the developing world, with special focus on sub-Saharan Africa
20 HIV and TB in industrialized countries
21 Tuberculosis and migration
PART 6 PREVENTION
22 Preventive therapy
23 Clinical interpretation of tests for latent tuberculosis infection
24 BCG vaccination
PART 7 CONTROL
25 Control of tuberculosis in low-prevalence countries
26 Control of tuberculosis in high-prevalence countries
27 The role of the specialist TB nurse
28 Global Plan to Stop TB 2006-2015
PART 8 RELATED ASPECTS
29 Environmental mycobacteria
30 Animal tuberculosis
PART 9 CONCLUSIONS
31 Conclusions