Genetics From Genes to Genomes

Description

Genetics: From Genes to Genomes is a cutting-edge, introductory genetics text authored by an unparalleled author team, including Nobel Prize winner, Leland Hartwell. The Second Edition continues to build upon the integration of Mendelian and molecular principles, providing students with the links between early genetics understanding and the new molecular discoveries that have changed the way the field of genetics is viewed.

Contents

1 Genetics: The Study of Biological Information
Part 1 Basic Principles: How Traits Are Transmitted
2 Mendel's Breakthrough: Patterns, Particles, and Principles of Heredity
3 Extensions to Mendel: Complexities in Relating Genotype to Phenotype
4 The Chromosome Theory of Inheritance
5 Linkage, Recombination, and the Mapping of Genes on Chromosomes
Part 2 What Genes Are and What They Do
6 DNA: How the Molecule of Heredity Carries, Replicates, and Recombines Information
7 Anatomy and Function of a Gene: Dissection Through Mutation
8 Gene Expression: The Flow of Genetic Information from DNA via RNA to Protein
Part 3 Genomes
9 Deconstructing the Genome: DNA at High Resolution
10 Reconstructing the Genome Through Genetic and Molecular Analysis
11 The Direct Detection of Genotype Distinguishes Individual Genomes
Part 4 How Genes Travel
12 The Eukaryotic Chromosome: An Organelle for Packaging and Managing DNA
13 Chromosomal Rearrangements and Changes in Chromosome Number Reshape Eukaryotic Genomes
14 The Prokaryotic Chromosome: Genetic Analysis in Bacteria
15 The Chromosomes of Organelles Outside the Nucleus Exhibit Non-Mendelian Patterns of Inheritance
Part 5 How Genes Are Regulated
16 Gene Regulation in Prokaryotes
17 Gene Regulation in Eukaryotes
18 Cell-Cycle Regulation and the Genetics of Cancer
19 Using Genetics to Study Development
Part 6 How Genes Change
20 The Genetic Analysis of Populations and How They Evolve
21 Evolution at the Molecular Level
Reference: Portraits of Model Eukaryotic Organisms
A Saccharomyces cerevisiae: Genetic Portrait of Yeast
B Arabidopsis thaliana: Genetic Portrait of a Model Plant
C Caenorhabditis elegans: Genetic Portrait of a Simple Multicellular Organism
D Drosophila melanogaster: Genetic Portrait of the Fruit Fly
E Mus musculus: Genetic Portrait of the House Mouse
Guidelines for Gene Nomenclature
Brief Answer Section