Molecular Biology Principles and Practice

Written and illustrated with unsurpassed clarity, Molecular Biology: Principles and Practice introduces fundamental concepts while exposing students to how science is done. The authors convey the sense of joy and excitement that comes from scientific discovery, highlighting the work of researchers who have shaped - and who continue to shape - the field today.

Contents:
PART I: FOUNDATIONS
Studying the Molecules of Life
DNA: The Repository of Biological Information
Chemical Basis of Information Molecules
Protein Structure
Protein Function

PART II: NUCLEIC ACID STRUCTURE & METHODS
DNA and RNA Structure
Studying Genes
Genomes, Transcriptomes, and Proteomes
Topology: Functional Deformations of DNA
Nucleosomes, Chromatin, and Chromosome Structure

PART III: INFORMATION TRANSFER
DNA Replication
DNA Mutation and Repair Moment of Discovery
Homologous Recombination
Site-Specific Recombination and Transposition
DNA-Dependent Synthesis of RNA
RNA Processing
The Genetic Code
Protein Synthesis

PART IV: REGULATION
Regulating the Flow of Information
The Regulation of Gene Expression in Bacteria
Transcriptional Regulation of Gene Expression in Eukaryotes
Post-Transcriptional Regulation of Gene Expression in Eukaryotes
Gene Regulation in Development
Online Appendix: Model Organisms