Motor Neuron Disease

Motor Neuron Disease is a state of the art monograph designed for the clinician who wants to stay on the cutting edge of the scientific understanding of motor neuron disease. The three most common motor neuron diseases are covered, namely sporadic amyotrophic lateral sclerosis, familial amyotrophic lateral sclerosis and childhood spinal muscular atrophy.

Succinct, well referenced and supported by appropriate illustrations the scope of the book includes current accepted diagnostic criteria for ALS, including practical case histories to aid differential diagnosis. The most common theories of pathogenesis are examined, and the most up to date review of the genetic implications for familial ALS included. A chapter on treatment includes coverage of the latest anti-excitotoxic drugs, in addition, a chapter on both management and support of the patient from the MND team is included. The book concludes with a review of the current trials , drug development and regulatory oversight and a look to the future and what therapies may be available in years to come.

This book will appeal to neurologists and all those involved in the treatment and management of the patient with motor neuron disease as an easy to read review of current developments and trends in this challenging and fast moving field.

Features

# An excellent overview of the current key issues surrounding motor neuron disease
# Explains the latest genetic developments clearly and with supporting illustrations
# Clinically relevant, includes some case histories
# Focuses on the three most common motor neuron diseases
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Contents

Essentials of Diagnosis
Errors in Diagnosis
Current Concepts in Pathogenesis of ALS
Genetics of ALS
Spinal Muscular Atrophy
Pharmacotherapy and its Scientific Basis
Multidisciplinary Approach to Management and Support of Patients
Therapeutic Trials, Drug Development and Regulatory Oversight
Future Therapy