Neurological Therapeutics: Principles and Practice

With over 600 figures and tables, Neurological Therapeutics: Principles and Practice is a fully updated three-volume text, available both as a hardback and in web-formats, to be used as important reference for treatment decisions in offices of neurological practice, clinics and hospitals.

Providing a reference that is both authoritative and accessible for daily use, key features of this evidence-based, highly acclaimed work include:

* more than 2750 major topics covering the vast patient mix primarily treated by adult and pediatric neurologists
* the most current definitive medical citations
* section editors who are all internationally recognized leaders in their fields
* new chapters addressing the important issues of stem cell therapy, pharmacogenomics, palliative care, the management of the organ donor, metabolic myelopathy, superficial siderosis and attention deficit hyperactivity disorder
* focus on the issues underlying treatment decisions not only for the most readily treated disorders but also for conditions with few existing, definitive therapeutic options
* comprehensive summary tables and informative figures, with the most recent supporting recommendations to guide treatment decisions for effective and efficient patient management in the busy clinic setting.

Building upon the success of its predecessor, this important second edition continues to address the need for a comprehensive textbook focused primarily on therapeutics, and will help busy students, clinicians and clinician-scientists in understanding the current status of neurological therapeutics in planning the care of their patients.

Table of Contents

Section 1: Principles of Therapeutics. 1. Basic Pharmaceutical Principles and the Blood-Brain Barrier 2. Molecular Therapies for the Nervous System and Muscle 3. Clinical Trial Methodology, FDA Terminology and Procedures 4. Placebo Analgesia 5. Evidence-Based Medicine 6. Ethical Issues in Neurological Treatment and Clinical Trials 7. Domestic Violence in Neurological Practice 7a. Palliative Care and Hospice 7b. Stem Cells Section 2: Pain: Headache, Spine and Limb Pain. 8. Principles of Pain Management 9. Migraine 10. Cluster Headaches 11. Tension-Type Headache 12. Chronic Daily Headache 13. Post-Traumatic Headache 14. Indomethacin-Responsive Headache Syndromes 15. Giant Cell Arteritis 16. Headache “Syndromes” in Children and Adolescents 17. Diagnosis and Treatment of Common Orofacial Pain Conditions 18. Radicular Limb Pain 19. Back Pain 20. Complex Regional Pain Syndrome (Reflex Sympathetic Dystrophy, Cuasalgia, Shoulder-Hand Syndrome) 21. The Treatment of Central Pain 22. Peripheral (Neuropathic) Pain Disorders 23. Cancer Pain 24. Fibromyalgia and Myofascial Pain Syndrome 25. Pain Disorder Section 3: Seizure Disorders 26. Classification and Epidemiology of Seizure Disorders: Therapeutic Implications and Importance 27. Pathophysiology of the Epilepsies 28. Principles in Epilepsy: Differential Diagnosis and Pharmacotherapy 29. Antiseizure Drugs 30. Surgery and Non-Pharmacological Therapies for Epilepsy 31. Status Epilepticus 32. The Treatment of Epilepsy in Children and Infants 33. Seizures and Epilepsy in Women 34. Imitators of epilepsy 35. Legal and Regulatory Issues for People with Epilepsy Section 4: Cerebrovascular Disease 37. Principles of Atherosclerosis and Atherogenesis 38. Stroke Prevention 38. Anticoagulant Therapy and Antiplatelet Drugs 39. Thrombolytic Therapy for Stroke 40. Asymptomatic Carotid Artery Stenosis 41. Transient Ischemic Attacks 42. Management of Patients with Acute Ischemic Stroke 43. Cardioembolic Stroke 44. Cerebral Complications after Cardiac Surgery and Cardiac Arrest 45. Hypoxic-Ischemic Encephalopathy 46. Treatment of Intracerebral Hemorrhage 47. Subarachnoid Hemorrhage Due to Cerebral Aneurysms 48. Cerebral Aneurysms and Vascular Malformations 49. Unruptured Intracranial Aneurysms 50. Cervicocephalic Arterial Dissections 51. Fibromuscular Dysplasia 52. Venous Disorders 53. Spinal Cord Vascular Syndromes 54. Disorders of Coagulation 55. Antiphospholipid Antibodies and Variants 56. Hypertensive Encephalopathy 57. Cerebral Autosomal Dominant Arteriopathy with Subcoritical Infarcts and Leukoencephalopathy (CADASIL) 58. Moyamoya Disease 59. Stroke in Children 60. Stroke in Pregnancy 61. Superficial Siderosis Section 5: Neuro-oncology 62. A Perspective on Neuro-oncology 63. Chemotherapy and Antineoplastic Agents 64. Radiotherapy for CNS Neoplasms: Principles, Technologies and Indications 65. Surgically Curable Brain Tumors of Adults 66. Diagnosis and Treatment of Pituitary Tumors 67. Diffuse Cerebral Gliomas in Adults 68. Malignant Brain Tumors of Childhood 69. Germ Cell Tumors and Primary Central Nervous System Lymphoma 70. Brain Metastases