Pathophysiology, The Biologic Basis for Disease in Adults and Children

Well-known for its authoritative and comprehensive coverage, complete treatment of pediatric pathophysiology, and the most extensive illustration program in its field, this textbook features expert content on everything from the general principles of pathophysiology to detailed discussions of genetics and specific diseases. Chapters on alteration present the pathophysiology, clinical manifestations, and evaluation and treatment of each disease to help you learn to identify normal anatomy and physiology, as well as alterations of function in adults and in children.

Pathophysiology, The Biologic Basis for Disease in Adults and Children, 6th Edition

By Kathryn L. McCance, RN, PhD and Sue E. Huether, RN, PhD

Introduction to Pathophysiology

PART ONE: CENTRAL CONCEPTS OF PATHOPHYSIOLOGY: CELLS AND TISSUES

Unit I: The Cell

1. Cellular Biology

2. Altered Cellular and Tissue Biology

3. The Cellular Environment: Fluids and Electrolytes, Acids and Bases

Unit II: Genes and Gene-Environment Interaction

4. Genes and Genetic Diseases

5. Genes, Environment, Life-style, and Common Diseases

Unit III: Mechanisms of Self-Defense

6. Innate Immunity: Inflammation

7. Adaptive Immunity

8. Alterations in Immunity and Inflammation

9. Infection

10. Stress and Disease

Unit IV: Cellular Proliferation: Cancer

11. Biology, Clinical Manifestations, and Treatment of Cancer

12. Cancer Epidemiology

13. Cancer in Children

PART TWO: PATHOPHYSIOLOGIC ALTERATIONS: ORGANS AND SYSTEMS

Unit V: The Neurologic System

14. Structure and Function of the Neurologic System

15. Pain, Temperature Regulation, Sleep, and Sensory Function

16. Alterations in Cognitive Systems, Cerebral Hemodynamics and Motor Function

17. Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction

18. Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders

19. Alterations of Neurologic Function in Children

Unit VI: The Endocrine System

20. Mechanisms of Hormonal Regulation

21. Alterations of Hormonal Regulation

Unit VII: The Reproductive Systems

22. Structure and Function of the Reproductive Systems

23. Alterations of the Reproductive Systems

24. Sexually Transmitted Infections

Unit VIII: The Hematologic System

25. Structure and Function of the Hematologic System

26. Alterations of Erythrocyte Function

27. Alterations of Leukocyte, Lymphoid, and Hemostatic Function

28. Alterations of Hematologic Function in Children

Unit IX: The Cardiovascular and Lymphatic Systems

29. Structure and Function of the Cardiovascular and Lymphatic Systems

30. Alterations of Cardiovascular Function

31. Alterations of Cardiovascular Function in Children

Unit X: The Pulmonary System

32. Structure and Function of the Pulmonary System

33. Alterations of Pulmonary Function

34. Alterations of Pulmonary Function in Children

Unit XI: The Renal and Urologic System

35. Structure and Function of the Renal and Urologic Systems

36. Alterations of Renal and Urinary Tract Function

37. Alterations of Renal and Urinary Tract Function in Children

Unit XII: The Digestive System

38. Structure and Function of the Digestive System

39. Alterations of Digestive Function

40. Alterations of Digestive Function in Children

Unit XIII: The Musculoskeletal System

41. Structure and Function of the Musculoskeletal System

42. Alterations of Musculoskeletal Function

43. Alterations of Musculoskeletal Function in Children

Unit XIV: The Integumentary System

44. Structure, Function, and Disorders of the Integument

45. Alterations of the Integument in Children

Unit XV: Multiple Interacting Systems

46. Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults

47. Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children