Principles of Medical Biochemistry; With STUDENT CONSULT Online Access

This is to-the-point medical student principles of biochemistry book that all health professional students can use. It is clinical oriented with new information of molecular biology and new content in medical genetics.


Features

# Half the length of a traditional "science" biochemistry book
# Half the cost of a traditional "science" biochem book
# Clinically oriented
# Increased content in molecular biology
# Increased coverage of genetics
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What's New

# Increased content in molecular biology
# Increased coverage of genetics
# Clinical cases in the text as well as in the back of the book
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Contents

Table of Contents

Part One: Principles of Molecular Structure and Function.

Chapter 1: Introduction to Biomolecules.

WATER: THE SOLVENT OF LIFE.
COVALENT BONDS AND NONCOVALENT INTERACTIONS
THE MAJOR CLASSES OF BIOMOLECULES.

Chapter 2: Protein structure.

THE AMINO ACIDS.
LEVELS OF PROTEIN STRUCTURE
THE PHYSICAL PROPERTIES OF PROTEINS

Chapter 3: Oxygen Transporters: Hemoglobin and Myoglobin.

Chapter 4: Enzymatic Reactions.

THERMODYNAMICS
ENZYME KINETICS
ENZYME INHIBITION
REACTION TYPES AND REACTION MECHANISMS

Chapter 5: Coenzymes

Part Two: Cell and Tissue Structure.
Chapter 6: Biological Membranes.

THE LIPID BILAYER.
MEMBRANE PROTEINS.
MEMBRANE TRANSPORT.
Chapter 7: The Cytoskeleton

Chapter 8: The Extracellular Matrix.
FIBROUS PROTEINS OF THE EXTRACELLULAR MATRIX.
THE AMORPHOUS GROUND SUBSTANCE

Part Three: Genetic Information: DNA, RNA, and Protein Synthesis.
Chapter 9: DNA, RNA, and Protein Synthesis: The Central Dogma of Molecular Biology.
DNA STRUCTURE AND DNA REPLICATION.
RNA AND THE GENETIC CODE.
PROTEIN SYNTHESIS.
REGULATION OF GENE EXPRESSION.

Chapter 10: Viruses

Chapter 11: The Human Genome and Its Expression.
CHROMATIN STRUCTURE.
THE ARCHITECTURE OF THE HUMAN GENOME.
TRANSCRIPTION AND TRANSLATION.
Chapter 12: The processing and targeting of proteins.
Chapter 13: Introduction to Genetic Diseases.

MUTATIONS AND DNA REPAIR.
THE HEMOGLOBINOPATHIES.

Chapter 14: DNA Technology.

THE TOOLS.
THE DIAGNOSIS OF GENETIC DISORDERS.
CLONING IN MICROORGANISMS.
GENE THERAPY.

Part Four: Signaling and signaling cascades.

Chapter 15: The Blood.

THE COMPONENTS OF PLASMA
PLASMA PROTEINS.
THE IMMUNOGLOBULINS.
THE BLOOD CLOTTING SYSTEM.
CLINICAL LABORATORY DIAGNOSIS.

Chapter 16: Extracellular Messengers.

THE STEROID HORMONES.
THE THYROID HORMONES.
THE BIOGENIC AMINES
PEPTIDES AND PROTEINS
THE EICOSANOIDS
NEUROTRANSMITTERS.
Chapter 17: Intracellular Messengers.

RECEPTORS.
G PROTEINS, SECOND MESSENGERS, AND PROTEIN KINASES.
RECEPTORS WITH ENZYMATIC ACTIVITIES.

Chapter 18: Cellular Growth Control and Cancer.
CELL CYCLE CONTROL.
MITOGENIC SIGNALING.
SOMATIC MUTATIONS AND CANCER.
SPECIFIC CANCERS.

Part Five: Metabolism.

Chapter 19: Digestive Enzymes.

Chapter 20: Introduction to Metabolism.

Chapter 21: The Oxidation of Glucose: Glycolysis, the TCA Cycle, and Oxidative Phosphorylation.

GLYCOLYSIS: FROM GLUCOSE TO PYRUVATE.
PYRUVATE DEHYDROGENASE AND THE TCA CYCLE: FROM PYRUVATE TO CARBON DIOXIDE AND REDUCED COENZYMES.
THE RESPIRATORY CHAIN AND OXIDATIVE PHOSPHORYLATION.
INHIBITION OF OXIDATIVE METABOLISM

Chapter 22: Carbohydrate Metabolism.

GLUCONEOGENEIS.
GLYCOGEN METABOLISM.
THE METABOLISM OF FRUCTOSE AND GALACTOSE.
THE MINOR PATHWAYS OF CARBOHYDRATE METABOLISM.

Chapter 23: The Metabolism of Fatty Acids and Triglycerides.

THE GENERATION OF METABOLIC ENERGY FROM FATTY ACIDS.
FROM CARBOHYDRATE TO FAT.

Chapter 24: The Metabolism of Membrane Lipids.

THE METABOLISM OF PHOSPHOGLYCERIDES AND SPHINGOLIPIDS.
CHOLESTEROL METABOLISM.

Chapter 25: Lipid Transport.

THE HIGHWAYS OF LIPID TRANSPORT.
LIPOPROTEINS AND ATHEROSCLEROSIS.
Chapter 26: Amino Acid Metabolism.
THE FATE OF THE AMINO NITROGEN.
AMINO ACID DEGRADATION.

Chapter 27: Heme Metabolism.

Chapter 28: The Metabolism of Purines and Pyrimidines.

Chapter 29: Vitamins and Minerals.

THE WATER-SOLUBLE VITAMINS.
THE FAT-SOLUBLE VITAMINS.
THE TRACE MINERALS.

Chapter 30: Integration of Metabolism.

HORMONAL REGULATION.
FEEDING AND FASTING
DIABETES MELLITUS.
PHYSICAL EXERCISE.
THE METABOLISM OF XENOBIOTICS.