Textbook of Pediatric Rheumatology

The only reference of its kind in the field ! The new edition of this definitive resource examines the full spectrum of rheumatologic diseases and non-rheumatologic musculoskeletal disorders in children and adolescents. It describes the presentation, differential diagnosis, course, management, and prognosis of every major condition. Drs. Cassidy and Petty have meticulously revised their masterwork to integrate important new scientific advances and clinical developments.
Reviews

Textbook of Paediatric Rheumatology Cassidy, Petty, Laxter, and Lindsley Book Review – Dr Simon Fountain-Polley Paediatric rheumatology is often a mysterious specialty for the uninitiated, containing a number of diseases with a reputation for being unusual and rare. However, collectively the rheumatological conditions are not that uncommon, and most clinicians will have seen children afflicted by them. Cassidy et al’s book is one way to tackle these conditions and explore paediatric rheumatology in a comprehensive way. The book is well written by several of the recognised experts in the world of paediatric rheumatology. As every good textbook should, it starts with a basic introduction to the subject then works its way around the underlying anatomical and immunological concepts required to understand the disease processes. The burgeoning knowledge and importance of individual and population genetics is reviewed and explained, and another chapter discusses the sometimes unfamiliar drugs used for children and adolescents with inflammatory conditions. A useful chapter revises the concepts behind clinical investigations rounds off the initial ground work. The rest of the book concentrates on the assessment and management of all the musculo-skeletal inflammatory and non-inflammatory disorders of childhood. Each group of diseases are placed into context and then described and discussed. There are many tables and figures to aid understanding and consolidate learning. The only slight problem is the occasional lack of consistency in the terms used for the now accepted Juvenile Idiopathic arthritis. Overall the Textbook of Paediatric Rheumatology will retain its place as the standard for its subject.
Key Features

* Features exhaustive reviews of the major clinical syndromes, describing the complex web of symptoms, signs, and lab abnormalities characteristic of these disorders in order to make diagnosis and treatment easier.
* Grounds treatment protocols in the best scientific evidence available today.
* Establishes an internationally accepted nosography of classification criteria based on the ACR, EULAR, and ILAR criteria.
* Clarifies complex concepts and demonstrates key techniques with 400 illustrations, which include new figures and a new four-color insert.
* Integrates the knowledge and experience of the founding fathers of pediatric rheumatology as well as a who's who of international experts in the field.

New to this Edition

* Expanded coverage of immunogenetics, detailing advances from the sequencing of the human genome and a new understanding of immunologic mechanisms of inflammatory disease.
* Enhanced discussions of pharmacology, drug therapy, and systemic connective tissue diseases.
* A new chapter on The Febrile Syndromes.
* The expertise of two new associate editors, Ronald M. Laxler and Carol B.Lindsley.

Table of Contents

BASIC CONCEPTS 1

C H A P T E R 1 Introduction to the Study of Rheumatic

C H A P T E R 2
Structure and Function

C H A P T E R 3
The Immune System and the Inflammatory
Response

C H A P T E R 4
Integrative Genomics

C H A P T E R 5
Pharmacology and Drug Therapy

C H A P T E R 6
Design, Measurement and Analysis of Clinical
Investigations

C H A P T E R 7
Assessment of Health Status, Function and
Quality of Life Outcomes: Methodology and
Instruments

C H A P T E R 8
A General Approach to Management of Rheumatic Disease in Children

C H A P T E R 9
Chronic Arthritis in Childhood

C H A P T E R 1 0
Polyarthritis

C H A P T E R 1 1
Oligoarthritis

C H A P T E R 1 2
Systemic Arthritis

C H A P T E R 1 3
Juvenile Ankylosing Spondylitis

C H A P T E R 1 4
Psoriatic Arthritis

C H A P T E R 1 5
Arthropathies of Inflammatory Bowel
Disease

C H A P T E R 1 6
Systemic Lupus Erythematosus

C H A P T E R 1 7
Neonatal Lupus Erythematosus

C H A P T E R 1 8
Juvenile Dermatomyositis

C H A P T E R 1 9
The Systemic Sclerodermas and Related
Disorders

C H A P T E R 2 0
Localized Sclerodermas

C H A P T E R 2 1
Overlap Syndromes

C H A P T E R 2 2
Vasculitis and its Classification

C H A P T E R 2 3
Leukocytoclastic Vasculitis

C H A P T E R 2 4
Polyarteritis Nodosa and Related

C H A P T E R 2 5
Kawasaki Disease

C H A P T E R 2 6
Granulomatous Vasculitis, Giant Cell Arteritis
and Sarcoidosis

C H A P T E R 2 7
Behcet’s Disease

C H A P T E R 2 8 Infectious Arthritis and Osteomyelitis

C H A P T E R 2 9 Lyme Disease

C H A P T E R 3 0 Reactive Arthritis
Ruben Burgos-Vargas and Janitzia Vazquez-Mellado

C H A P T E R 3 1
Acute Rheumatic Fever and Post-streptocococcal

C H A P T E R 3 2
Musculoskeletal Manifestations of Systemic
Disease

C H A P T E R 3 3
Immunodeficiencies and the Rheumatic
Diseases

C H A P T E R 3 4
Periodic Fever Syndromes in Children

C H A P T E R 3 5
Cryopyrin associated Periodic Syndrome

C H A P T E R 3 6
Noninflammatory Musculoskeletal Pain
Conditions

C H A P T E R 3 7
Pain and the Pain Amplification Syndromes


C H A P T E R 3 8
Skeletal Maturation and Bone Mineralization in
the Pediatric Rheumatic Diseases


C H A P T E R 3 9
Skeletal Malignancies and Related Disorders


C H A P T E R 4 0
Primary Disorders of Bone and Connective
Tissues