english version

Animal Models in Toxicology

Preț: 525,00 lei
Disponibilitate: în stoc
Autor:
ISBN: 9780824754075
Anul publicarii: 2006
Ediția: 2
Pagini: 952
Categoria: TOXICOLOGY

DESCRIERE

# Provides tables of normative physiology, pathology, reproductive, clinical laboratory, and metabolism data
# Presents detailed discussions of husbandry, major diseases, and handling for the major species used in toxicology and experimental biology
# Contains detailed descriptions and illustrations for dosing, blood collection, and other procedures
# Reviews current laws and regulations governing animal care and use in major countries
# Includes extensive appendices of acronyms, regulatory and scientific Web sites, animal suppliers, and a lexicon of terms used in describing clinical signs


Reflecting more than a decade's worth of changes, Animal Models in Toxicology, Second Edition is a practical guide to the common statistical problems encountered in toxicology and the methodologies that are available to solve them. The book presents a historical review of the use of animal models and an overview of broad considerations of metabolism and relevance used in toxicology. Individual chapters covering the eight major species used in toxicology and experimental biology form the core of the book. With contributions from experts in toxicology, toxicological pathology, and species-specific metabolism, each of these chapters provide an excellent introductory "course" along with guidance to the literature for more detailed understanding.

The book goes on to make the case for a range of species not commonly used for safety assessment studies but which may provide useful alternative models for some specific endpoints. The chapter authors discuss special considerations regarding the evaluation and interpretation of the clinical pathology of the eight major model species as well as how to select a model species and how to extrapolate the results to humans. They detail potential pitfalls and situations that cause either human or model to be significantly more sensitive than the other or totally irrelevant to each other. The book concludes with an overview of the increasingly complex laws and regulations that govern how laboratory animals are obtained, maintained, and utilized, and an appendix that provides a quick guide to commercial sources of laboratory animals.

REVIEW-URI

Spune-ne opinia ta despre acest produs! scrie o recenzie

Cărți noi - TOXICOLOGY

Created in 0.0544 sec
Acest site folosește cookie-uri pentru a permite plasarea de comenzi online, precum și pentru analiza traficului și a preferințelor vizitatorilor. Vă rugăm să alocați timpul necesar pentru a citi și a înțelege Politica de Cookie, Politica de Confidențialitate și Clauze și Condiții. Utilizarea în continuare a site-ului implică acceptarea acestor politici, clauze și condiții.