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Fibrinolytic and Antithrombotic Therapy, Theory, Practice, and Management

Fibrinolytic and Antithrombotic Therapy, Theory, Practice, and Management
Preț: 262,50 lei
Disponibilitate: în stoc la furnizor
Autor:
ISBN: 978-0-19-515564-8
Anul publicarii: 2006
Ediția: 2
Pagini: 424

DESCRIERE

Reviews * 'This pocket-sized book is full of integrated insights into hemostasis and vital information on fibrinolytic and antithrombotic therapy. The author writes in easy-to-understand language and supplements his text with appropriately placed figures, graphs, tables, EKGs, and algorithms tailored to the needs of practicing clinicians, cardiologists, emergency room physicians, hematologists, and nurses.' - Doody's Reviews Description Thrombotic disorders of the circulatory system represent the leading cause of morbidity, motality, and health care expenditure in the United States. Fibrinolytic and Antithrombotic Therapy provides a practical, evidence-based approach to the management of thrombotic disorders for all clinicians involved in the care of patients with these disorders. It provides not only vital conceptual information on fibrinolytic and antithrombotic therapy, but also the means to apply it to everyday decision making and patient care. Focusing on management guidelines and critical pathways, the text stresses practicality and usability. It will be a valuable resource for the wide range of clinicians involved in the care of patients with these disorders, including cardiologists, emergency physicians, primary care physicians, haematologists, neurologists, intensivists, pharmacists, and nurse practitioners. The origins of mammalian blood coagulation can be traced back over 400 million years. Despite its long history, it is only within the past century that this complex and pivotal teleologic system has begun to be understood. Most recently, the intricacies of haemostasis and pathologic thrombosis have come to light, leading the way toward new, more effective, and safer treatment modalities. The Second Edition of Fibrinolytic and Antithrombotic Therapy, even more concise and clinically relevant than the First, provides vital, evidence-based information on management of patients with arterial and venous thrombotic disorders. Since the First Edition, the text has been expanded to cover the evolving topics of atherothrombosis, thrombocardiology, haematologic/thrombophilic conditions, and vascular medicine. It includes up-to-date guidelines for antithrombotic and fibrinolytic therapy, and offers concise summaries of current "standards of care." Chapters are dedicated to discussions of patient-specific therapeutics and to the importance of genomics, proteomics, and metabolomics in defining genotype-phenotype relationships, while throughout the book coagulation, inflammation, and vascular medicine are newly examined as elements in an intricately-linked triad of biochemical and cellular based phenomenology. Contents Part I: Fundamental Scientific Principles 1. Historical Perspectives of Hemostasis, Coagulation, and Fibrinolysis 2. Vascular Biology, Thromboresistance and Inflammation 3. Atherosclerosis and Arterial Thrombosis 4. Venous Thromboembolism 5. Cardiac Chamber, Aortic and Valvular Thromboembolism Part II: Fibrinolytics and Platelet Antagonists 6. Fibrinolytic Agents 7. Asprin 8. Clopidogrel 9. GPIIb/IIIa Receptor Antagonists 10. Aggrenox and Cilostazol 11. Novel Platelet Antagonists 12. Combination Pharmacotherapy 13. Facilitated Percutaneous Coronary Interventions Part III: Anticoagulants 14. Thrombin-Directed Therapy 15. Factor Xa Inhibitors 16. Direct Thrombin Inhibitors 17. Novel Anticoagulants Part IV: Management of Arterial Thrombotic Disorders 18. Acute Coronary Syndromes 19. Peripheral Vascular Disease and Stroke 20. Valvular Heart Disease and Atrial Fibrillation 21. Plaque Stabilizing Therapies Part V: Management of Venous Thrombotic Disorders 22. Venous Thromboembolism Prophylaxis 23. Venous Thromboembolism Treatment Part VI: Genomics, Proteomics and Suspected Thrombophilias 24. Fundamentals and Patient Evaluation Part VII: Monitoring Antithrombotic Therapy 25. Platelet Antagonists 26. Antocoagulants 27. Anticoagulation Clinics and Self-Testing Part VIII: Complication of Treatment and Their Management 28. Platelet Antagonists 29. Anticoagulants 30. Fibrinolytic Agents Appendix A. Pharmacopeia Platelet Antagonists Fibrinolytic Agents B. Drug Dosing with Renal Insufficiency Authors, editors, and contributors Richard C. Becker, Professor of Medicine, Duke University Medical Center and Frederick A. Spencer, Professor of Medicine in Cardiology and Hematology, McMaster University Faculty of Health Sciences

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